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Investing in CCP Games | Andreessen Horowitz https://a16z.com/announcement/investing-in-ccp-games/

Years before the first blockchain was created, the sci-fi space MMO EVE Online proved out many of the core principles that define web3 today. This is why we are excited to be partnering with CCP on a new project set in the EVE Universe. Context on EVE Online Released in 2003 by Icelandic developer ...

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The Open Source CIO | Andreessen Horowitz https://a16z.com/podcast/the-open-source-cio/

In 2014, in “Why There Will Never Be Another Red Hat,” Peter Levine argued that Red Hat’s open source business model of commercializing support and services was highly difficult to replicate. Instead, he predicted the future of open source companies would be open source-as-a-service. And today ...

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        desc: "Competition, send ‘em south. If they’re gonna drown put a hose in their mouth —Mark Knopfler, Boom Like That If you’re a physical retailer and you sell the same SKU’s as Amazon, you will not have a Happy Holiday this season. Starting with the hoopla around Black Friday and Cyber Monday, ...",
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When Black Friday Comes… | Andreessen Horowitz https://a16z.com/when-black-friday-comes/

Competition, send ‘em south. If they’re gonna drown put a hose in their mouth —Mark Knopfler, Boom Like That If you’re a physical retailer and you sell the same SKU’s as Amazon, you will not have a Happy Holiday this season. Starting with the hoopla around Black Friday and Cyber Monday, ...

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Bio Eats World: The Art and Science of Biology’s Future | Andreessen Horowitz https://a16z.com/podcast/bio-eats-world-the-art-and-science-of-biologys-future/

In this episode of Bio Eats World, we talk to Dr. Jennifer Doudna—winner of the 2020 Nobel Prize for the co-discovery (with Emmanuelle Charpentier) of CRISPR-Cas9—about the art and science of biology. Huge breakthroughs such as Doudna’s—which began with the identification of CRISPR in ...

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        desc: "A persistent problem in web3 today is the issue of scalability: as blockchains like Ethereum add users and experience unpredictable surges in network demand, they increasingly run into the same hitches of slow transaction times, high gas fees, and reverted transactions. Even as the number of ...",
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Investing in Matter Labs | Andreessen Horowitz https://a16z.com/announcement/investing-in-matter-labs/

A persistent problem in web3 today is the issue of scalability: as blockchains like Ethereum add users and experience unpredictable surges in network demand, they increasingly run into the same hitches of slow transaction times, high gas fees, and reverted transactions. Even as the number of ...

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        desc: "The precision medicine paradigm is a powerful one–for cancer patients, and for the entire oncology ecosystem. Over 50 targeted (‘tailored’ or ‘genome-informed’) oncology drugs have been approved by the FDA for clinical use since the 1990s, and propelled into practice with growing payor ...",
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Investing in Function Oncology | Andreessen Horowitz https://a16z.com/announcement/investing-in-function-oncology/

The precision medicine paradigm is a powerful one–for cancer patients, and for the entire oncology ecosystem. Over 50 targeted (‘tailored’ or ‘genome-informed’) oncology drugs have been approved by the FDA for clinical use since the 1990s, and propelled into practice with growing payor ...

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Investing in Orbital Therapeutics | Andreessen Horowitz https://a16z.com/announcement/investing-in-orbital-therapeutics/

Orbital is taking advantage of what is already known, but also innovating with urgency to make RNA-based therapeutics impactful and accessible for a much wider set of patients worldwide.

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        desc: "Last year, I wrote about our series B investment in Applied Intuition, which builds simulation software and infrastructure tools to safely test and validate autonomous vehicles at scale. Now, just a little over a year later, so much has changed — a global pandemic, among other things! — but ...",
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Applied Intuition Series C | Andreessen Horowitz https://a16z.com/announcement/applied-intuition-series-c/

Last year, I wrote about our series B investment in Applied Intuition, which builds simulation software and infrastructure tools to safely test and validate autonomous vehicles at scale. Now, just a little over a year later, so much has changed — a global pandemic, among other things! — but ...

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America Cannot Lose the Robotics Race | Andreessen Horowitz https://a16z.com/america-cannot-lose-the-robotics-race/

China has rapidly surpassed global competitors in robotics, building a complete supply chain and innovation ecosystem that positions it as the emerging superpower in physical AI. Without urgent regulatory reform and allied industrial coordination, the United States risks losing its ability to ...

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Notes on Leadership | Andreessen Horowitz https://a16z.com/notes-on-leadership/

What makes people want to follow a leader? We look for 3 key traits.

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        desc: "watch time: 2 minutes Looking at the sales pipeline means both qualifying and predicting your company’s future… every quarter. This video shares how founders can estimate in-quarter pipeline, without a crystal ball. You can watch this entire series\u{a0}of snack-sized videos, or mix-and-match your ...",
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Predicting Your Pipeline | Andreessen Horowitz https://a16z.com/predicting-your-pipeline/

watch time: 2 minutes Looking at the sales pipeline means both qualifying and predicting your company’s future… every quarter. This video shares how founders can estimate in-quarter pipeline, without a crystal ball. You can watch this entire series of snack-sized videos, or mix-and-match your ...

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Investing in Firstbase | Andreessen Horowitz https://a16z.com/announcement/investing-in-firstbase/

Last year most of us experienced working from home full-time for the first time, and not by choice. Within weeks, many of us realized we needed a better chair, and then a better desk, a monitor, a keyboard, better lighting, a laptop stand, a better camera. The knowledge workers of the world were ...

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        desc: "The entire history of the computing industry ebbs and flows between centralized and distributed computing. We started with mainframes with terminals on the end, so that everything ran centrally in the mainframe with the terminals as displays. Then, we moved to a more distributed client-server model ...",
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Cloud-Client Computing | Andreessen Horowitz https://a16z.com/cloud-client-computing/

The entire history of the computing industry ebbs and flows between centralized and distributed computing. We started with mainframes with terminals on the end, so that everything ran centrally in the mainframe with the terminals as displays. Then, we moved to a more distributed client-server model ...

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Investing in Sleeper | Andreessen Horowitz https://a16z.com/announcement/investing-in-sleeper/

Sports have long been a center of gravity for our social lives, bringing together friends, family, and fans. For many, sports are woven into our lives—we have childhood memories of watching baseball games with family, football games after a big Thanksgiving dinner, or tailgating a college football ...

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Investing in SeedFi | Andreessen Horowitz https://a16z.com/announcement/investing-in-seedfi/

There are over 100 million people in the U.S. living paycheck to paycheck. Seventy percent of Americans have less than $1,000 saved and 45 percent have no savings at all. For many Americans, this story will sound familiar: You’re squeaking by, then the inevitable happens—you get a flat tire. You ...

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Investing in Svix | Andreessen Horowitz https://a16z.com/announcement/investing-in-svix/

Every so often, we meet founders with unusually strong conviction about solving systems problems. They’ve often lived through the pain of bad software, diagnosed the cause of their suffering, and made it their mission to convince the world they have the right solution. Starting a company can be ...

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This Julep is Mint! | Andreessen Horowitz https://a16z.com/announcement/this-julep-is-mint/

We at a16z believe we are seeing the “creative destruction” of traditional physical retailers by their online competitors.  At a high level, this is happening for two reasons.  First, e-commerce companies are substantially advantaged in terms of cost structures, particularly in areas like real ...

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Investing in Asserts.ai | Andreessen Horowitz https://a16z.com/announcement/investing-in-asserts-ai/

With the rise of the cloud, we are witnessing a major transformation in how software is developed and maintained. As a developer, microservice architecture is quite appealing. It enables us to decouple singular monolithic software into a smaller set of services, making it possible for small teams of ...

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How to Build an AI-Native Health Plan with Mario Schlosser | Andreessen Horowitz https://a16z.com/podcast/how-to-build-an-ai-native-health-plan/

Mario Schlosser, cofounder, former CEO, and current President of Technology at Oscar Health, joins Julie Yoo of Bio + Health. The conversation explores how AI advancements can revolutionize traditional healthcare models by enhancing efficiency, personalizing care journeys, and integrating real-time ...

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Investing in EngFlow | Andreessen Horowitz https://a16z.com/announcement/investing-in-engflow/

Build is one of the most foundational tools for software engineering. Traditionally, it is the step in software development that takes the files written by engineers and compiles them into machine runnable code, but build has become so much more. Yes, it is used to compile code, but it is often the ...