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Going Deeper Into Freenome | Andreessen Horowitz https://a16z.com/announcement/going-deeper-into-freenome/

Due to the great work of researchers over the last decades, there are numerous drugs and surgical techniques to cure patients of cancer — if the cancer is caught early. And that’s notoriously hard to do, especially when symptoms often only arise in late stages of some of the most lethal cancers. ...

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How to Engineer Biology | Andreessen Horowitz https://a16z.com/how-to-engineer-biology/

Because biology is the result of evolution and not human development, bringing engineering principles to it is guaranteed to fail. Or so goes the argument behind the “Grove fallacy,” first invoked by drug industry observer Derek Lowe in a critique of Intel CEO Andy Grove in 2007. After being ...

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Top 10 a16z Live Conversations of 2021 | Andreessen Horowitz https://a16z.com/top-10-a16z-live-conversations-of-2021/

In 2021, we launched a16z Live to capture and share live discussions and events featuring, hosted, or co-hosted by a16z. Many of these different discussions and events take place on the social audio/ drop-in chat app Clubhouse, and here we round up ten of our favorites, covering many of the ...

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TikTok & Beyond: The Algorithm Question, The Future of Product | Andreessen Horowitz https://a16z.com/podcast/tiktok-beyond-the-algorithm-question-the-future-of-product/

With the U.S. tech partnership for TikTok being finalized, what happens if source code is excluded (and more specifically, the For You Page algorithm), given China’s revised export controls? But more broadly — well beyond the specifics and politics of this deal — what does the success of ...

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How to Hire a Chief of Staff | Andreessen Horowitz https://a16z.com/newsletter/how-to-hire-a-chief-of-staff/

a16z.com how to hire a chief of staff hacker news whatsapp reddit linkedin flipboard copy link facebook

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OpenGov: The Startup Analyzing $50B in Spending | Andreessen Horowitz https://a16z.com/announcement/opengov-the-startup-analyzing-50b-in-spending/

“A billion here, a billion there, and pretty soon you’re talking real money!” — attributed to Fmr. Sen. Everett Dirksen When an entrepreneur arrives with an active list of customers that have more than $50 billion in annual revenue, one tends to pay attention. Zachary Bookman had just such ...

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AnyRoad | Andreessen Horowitz https://a16z.com/announcement/anyroad/

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Announcement: Andreessen Horowitz Partners with Lilly to Launch First-of-Its-Kind Biotech Ecosystem ... https://a16z.com/announcement-andreessen-horowitz-partners-with-lilly-to-launch-first-of-its-kind-biotech-ecosystem-venture-fund/

Andreessen Horowitz (a16z) Bio + Health today announced a newly formed, first-of-its-kind venture capital fund to fuel broader innovation in human health, in partnership with Eli Lilly and Company (“Lilly”). The Biotech Ecosystem Venture Fund (“Fund”) seeks to drive transformative progress ...

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How 100 Enterprise CIOs Are Building and Buying Gen AI in 2025 https://a16z.com/ai-enterprise-2025/

16 key shifts in how enterprises are budgeting for, buying, and deploying gen AI in 2025—and beyond.

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AI is Industrializing Discovery | Andreessen Horowitz https://a16z.com/ai-is-industrializing-discovery/

One of the defining characteristics in an industrial revolution is the fundamental shift from a bespoke, artisan process to an  industrialized, engineerable, repeatable one. In this video, general partner on the Bio Fund Vijay Pande describes how we are in the middle of a revolution driven by AI ...

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“Death of a Salesforce”: Why AI Will Transform the Next Generation of Sales Tech | Andreessen ... https://a16z.com/ai-transforms-sales/

With LLMs and AI-enabled data infrastructure, common sales activities will be redefined and completely new seller workflows will emerge.

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Investing in LMArena: The Reliability Layer for AI | Andreessen Horowitz https://a16z.com/announcement/investing-in-lmarena-the-reliability-layer-for-ai/

LMArena began as a Berkeley research project and has quickly become essential infrastructure for evaluating large language models.

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Investing in Tackle | Andreessen Horowitz https://a16z.com/announcement/investing-in-tackle/

The most significant transformation in IT infrastructure over the last few decades, and the largest opportunity for enterprise companies I’ve seen in my lifetime, has been the move to cloud. It encompasses the shift of trillions of dollars of IT spend, and it has changed how we build, deploy, and ...

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        desc: "1. Institutional acceptance Patience, please — ‘legal’ Bitcoin is actually only one year old! That is, even though the Bitcoin source code was posted to the Internet in 2009, it was only clearly legal for American institutions to get involved with it after the IRS tax guidance was published in ...",
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Bitcoin (and Blockchain) | Andreessen Horowitz https://a16z.com/bitcoin-and-blockchain/

1. Institutional acceptance Patience, please — ‘legal’ Bitcoin is actually only one year old! That is, even though the Bitcoin source code was posted to the Internet in 2009, it was only clearly legal for American institutions to get involved with it after the IRS tax guidance was published in ...

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Investing in Orbit | Andreessen Horowitz https://a16z.com/announcement/investing-in-orbit/

Great communities make great companies, and community-building is now part of a broader shift in B2B businesses towards bottom-up growth. As part of that shift, companies are relying on communities as a key method for growing and engaging their user base, and moving from focusing on traditional ...

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Online Marketplaces | Andreessen Horowitz https://a16z.com/online-marketplaces/

We’re continuing to see tremendous innovation in marketplaces. The first generation of net companies saw a few big horizontal marketplace winners like eBay and Craigslist. But entrepreneurs are continuing to create the next generation of online marketplaces: …A ton of very interesting net ...

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CLF II | Andreessen Horowitz https://a16z.com/clf-ii/

When we launched the CLF three years ago, we decided to focus on two main missions: connecting the world’s greatest cultural leaders to the best new technology companies and bringing more African Americans into the technology industry. With the support of our LPs, portfolio companies, and our ...

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Investing in Sourcegraph | Andreessen Horowitz https://a16z.com/announcement/investing-in-sourcegraph/

If software is eating the world, code is swallowing companies whole. Whether living across multiple repositories or within a single monolith, an astonishing amount of code—and its associated languages, systems, and tools—has become a reality at not just scale tech players but at all companies. ...

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Investing in Material Security | Andreessen Horowitz https://a16z.com/announcement/investing-in-material-security/

My inbox holds more information about my online and offline life than any other repository. It holds access to my online accounts. It holds decades of conversations and documents around my financial, professional, academic and personal dealings. And in the name of modern cloud convenience, it is all ...

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Investing in Zus Health | Andreessen Horowitz https://a16z.com/announcement/investing-in-zus-health/

A Healthcare Internet, For Real This Time A couple of years ago I declared that we were finally in the ‘Netscape era of healthcare’. Online appointment scheduling, telehealth visits, and digital payments — all signs of a healthcare internet, right? Nope, I was wrong. It would have probably ...