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a16z Podcast: We Gotta Talk Pokémon Go | Andreessen Horowitz https://a16z.com/podcast/a16z-podcast-we-gotta-talk-pokemon-go/

Seemingly overnight, a single game — Pokémon Go — has taken people by storm. But it’s a game that was technically years in the making, building on a legacy of creative intellectual property and technologies such as mobile, geomapping/ geolocation, computer vision, and more. And since ...

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In the Vault: Assessing AI Impact vs. Hype with John Stecher of Blackstone | Andreessen Horowitz https://a16z.com/podcast/in-the-vault-john-stecher-blackstone/

Blackstone's CTO describes the qualities he looks for in early stage companies and predicts AI's impact on real estate, credit, and energy.

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The Frontier of Spatial Intelligence with Fei-Fei Li | Andreessen Horowitz https://a16z.com/podcast/the-frontier-of-spatial-intelligence-with-fei-fei-li/

Fei-Fei Li and Justin Johnson are pioneers in AI. While the world has only recently witnessed a surge in consumer AI, our guests have long been laying the groundwork for innovations that are transforming industries today. In this episode, a16z General Partner Martin Casado joins Fei-Fei and Justin ...

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Brains, Bodies, Minds … and Techno-Religions | Andreessen Horowitz https://a16z.com/podcast/a16z-podcast-brains-bodies-minds-and-techno-religions/

Evolution and technology have allowed our human species to manipulate the physical environment around us — reshaping fields into cities, redirecting rivers to irrigate farms, domesticating wild animals into captive food sources, conquering disease. But now, we’re turning that “innovative ...

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a16z Podcast: Compensation Isn’t About Paying the Most, It’s About Being Consistent | Andreessen ... https://a16z.com/podcast/a16z-podcast-compensation-isnt-about-paying-the-most-its-about-being-consistent/

The key to any great company is the people. Of course, part of attracting and keeping the best people is compensation. It seems straightforward, but if you don’t develop a philosophy early around how you are going to compensate all those great employees you’re going to be in a world of hurt ...

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a16z Podcast: ‘In the Eye of a Tornado’ — Views on Innovation from China | Andreessen Horowitz https://a16z.com/podcast/a16z-podcast-in-the-eye-of-a-tornado-views-on-innovation-from-china/

No matter how one views Xiaomi — and there are many ways to view it, for better or worse — one thing is clear: It, and other such companies (like WeChat and Alibaba), indicate a broader trend around innovation coming from China. Companies and countries that were once positioned as copycats or ...

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It’s Time to Build in Healthcare | Andreessen Horowitz https://a16z.com/podcast/its-time-to-build-in-healthcare/

Half of prescribed medications are never taken, and 88% of Americans are metabolically unhealthy. Despite spending 20% of our GDP on healthcare—twice that of any other developed nation—our outcomes still lag behind. In this episode, we explore why technologists must step into the healthcare ...

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AI, Robotics & the Future of Manufacturing | Andreessen Horowitz https://a16z.com/podcast/ai-robotics-the-future-of-manufacturing/

Marc and Ben continue their discussion on the “State of AI” as it relates to company building. In light of recent developments at Boeing, Marc and Ben commence the episode with a discussion on the real criteria boards utilize to select a CEO. Returning to the topic of AI, the two explore the ...

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Gross Margins, Early to Late: What They Do (and Don’t) Tell You | Andreessen Horowitz https://a16z.com/podcast/a16z-podcast-gross-margins-early-to-late-what-they-do-and-dont-tell-you/

Gross margins–which are essentially a company’s revenue from products and services minus the costs to deliver those products and services to customers–are one of the most important financial metrics for any startup and growing business. And yet, figuring out what goes into the “cost” for ...

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a16z Podcast: The Next Phase of 3D Printing | Andreessen Horowitz https://a16z.com/podcast/a16z-podcast-the-next-phase-of-3d-printing/

In this wide-ranging discussion about the latest and next consumer and industrial applications for 3D printing, we examine (with Shapeway’s Carine Carmy and a16z’s Tom Rikert): how the software-driven ideal of product-market-fit may be achieved in physical products, too — with rapid ...

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Founders Playbook: Lessons from Riot, Discord, & More | Andreessen Horowitz https://a16z.com/podcast/founders-playbook-lessons-from-riot-discord-more/

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From Surgeon to Biotech CEO with Jonathan Lim | Andreessen Horowitz https://a16z.com/podcast/from-surgeon-to-biotech-ceo-with-jonathan-lim/

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The Electrification of Everything: From Sky to Sea | Andreessen Horowitz https://a16z.com/podcast/the-electrification-of-everything-from-sky-to-sea/

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a16z Podcast: Capitalizing on an Autonomous Vehicle Future | Andreessen Horowitz https://a16z.com/podcast/a16z-podcast-capitalizing-on-an-autonomous-vehicle-future/

When people talk about autonomous vehicles, we hear everything from “we’re much closer than you think” to “we’re much further than you think”. So where are we, really, in the widespread reality of autonomous vehicles today? It depends, of course, on how you define autonomy — which is ...

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Evaluating AI in Bio: How to Know Whether it is Worth the Work | Andreessen Horowitz https://a16z.com/evaluating-ai-in-bio-how-to-know-whether-it-is-worth-the-work/

It’s Time to Heal is a special package about engineering the future of bio and healthcare. See more at: https://a16z.com/time-to-heal/. Given its immense potential utility, AI is now a part of every link on bio’s value chain, from drug discovery, to diagnostic development, to ...

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Scaling Your Technical Org | Andreessen Horowitz https://a16z.com/scaling-your-technical-org/

As your technical org starts “shipping its org chart,” how you structure the relationship between your product and engineering teams becomes key to scaling.

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a16z Podcast: The Why, How, and When of Sales | Andreessen Horowitz https://a16z.com/podcast/a16z-podcast-the-why-how-and-when-of-sales/

The hallmark of many great technical founder/CEOs is that they envision a better way of doing things, and that’s why they’re building a company that delivers on that better way, often disrupting the way things have always been done before. But this very mindset can backfire when it comes to ...

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Strategizing Channel Partnerships with Florian Otto | Andreessen Horowitz https://a16z.com/podcast/strategizing-channel-partnerships-with-florian-otto/

Today’s episode is with Florian Otto, cofounder and CEO of Cedar. He is joined by a16z Bio + Health general partner Julie Yoo.

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The Evolution of the Firm — with Ben and Marc | Andreessen Horowitz https://a16z.com/podcast/the-evolution-of-the-firm-with-ben-and-marc/

Recorded live at the 2025 a16z LP Summit, this episode is a candid conversation between a16z cofounders Marc Andreessen and Ben Horowitz—hosted by general partner Erik Torenberg. They cover the evolution of a16z from startup firm to multi-practice platform, how the media landscape is shaped by ...

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A Nuclear Comeback: Are New Reactors the Answer? | Andreessen Horowitz https://a16z.com/podcast/a-nuclear-comeback-are-new-reactors-the-answer/

Nuclear energy accounts for 20% of the electricity in the United States, but remarkably, 2023 marked the commissioning of the U.S.’s first new nuclear reactor in over three decades. The past few years have been a story of changing public opinion, but equally, innovative startups crafting ...