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The First Principles of Executive Hiring | Andreessen Horowitz https://a16z.com/the-first-principles-of-executive-hiring/

Building your executive team is key to scaling your company quickly and effectively. These first principles lay the foundation for making those key hires.

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Investing in OpenRouter | Andreessen Horowitz https://a16z.com/announcement/investing-in-openrouter/

OpenRouter is becoming the grid operator AI needs — offering a single API to access hundreds of LLMs, and handling failover, load balancing, and routing.

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Doing More with Moore: Biotech’s Tech Moment | Andreessen Horowitz https://a16z.com/doing-more-with-moore-biotechs-tech-moment/

The biotech industry’s appetite for science-native SaaS tools is accelerating and will modernize how medicines are discovered, developed, and distributed.

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16 Things to Know About the 409A Valuation | Andreessen Horowitz https://a16z.com/16-things-to-know-about-the-409a-valuation/

Everything you need to know about 409A valuations, including how they’re calculated, when to reevaluate, and the common myths and pitfalls.

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The Strategic Approach to Building a Board https://a16z.com/the-strategic-approach-to-building-a-board/

Building your board forward from product-market fit—instead of backward from an IPO date—makes it easier to find the right advisors at the right time as you scale.

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Putting Data in a Corner: LLMs and Financial Services Data | Andreessen Horowitz https://a16z.com/putting-data-in-a-corner-llms-and-financial-services-data/

3 financial service giants cornered the market on data at the dawn of the digital age. What can founders learn from them?

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For B2B Generative AI Apps, Is Less More? | Andreessen Horowitz https://a16z.com/for-b2b-generative-ai-apps-is-less-more/

We’ve watched large language models (LLMs) become mainstream over the past few years and have studied the implementations in the context of B2B applications. Despite some enormous technological advances and the presence of LLMs in the general zeitgeist, we believe we’re still only in the first ...

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How Generative AI Is Remaking UI/UX Design | Andreessen Horowitz https://a16z.com/how-generative-ai-is-remaking-ui-ux-design/

Mature code-generation technology, coupled with advanced generative AI image models, has shortened the journey from idea to fully operational application.

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The Digital Future of Tabletop Games | Andreessen Horowitz https://a16z.com/the-digital-future-of-tabletop-games/

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The Insider’s Guide to Data Rooms: What to Know Before You Raise | Andreessen Horowitz https://a16z.com/the-insiders-guide-to-data-rooms-what-to-know-before-you-raise/

It’s time for your startup to fundraise. You prepare a deck, practice your pitch, and start reaching out to investors. If a first meeting goes well, it often ends with a request to share your “data room.” But what is a data room, and what should be included in it? What is a data room?...

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The Four Horsemen of Centralization | Andreessen Horowitz https://a16z.com/the-four-horsemen-of-centralization/

What does it mean to say that a cryptonetwork is decentralized? A quick Twitter search suggests that it has to do with how many computers are running in it, the number of miners keeping it secure, their respective hashing power, or the degree to which such things are all geographically strewn about. ...

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Voice AI Will Change How We Bank (February 2025 Fintech Newsletter) | Andreessen Horowitz https://a16z.com/newsletter/voice-ai-will-change-how-we-bank-february-2025-fintech-newsletter/

For voice agents in finance to become successful, they will need to navigate a number of industry-specific nuances.

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The Empty Promise of Data Moats | Andreessen Horowitz https://a16z.com/the-empty-promise-of-data-moats/

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AI + a16z with Vijay Pande | Andreessen Horowitz https://a16z.com/podcast/ai-a16z-with-vijay-pande/

Vijay Pande, PhD, founding partner of a16z Bio + Health, joins Derrick Harris, host of the AI + a16z podcast.

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Investing in [untitled] | Andreessen Horowitz https://a16z.com/announcement/investing-in-untitled/

[untitled] is building the new operating system for musicians. Users can upload, organize, and even edit their music on mobile with AI-powered features.

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Merging Glam and Ning | Andreessen Horowitz https://a16z.com/merging-glam-and-ning/

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What I’ve Been Up To Lately | Andreessen Horowitz https://a16z.com/what-ive-been-up-to-lately/

An Internet news outlet is asking a lot of people I know, and some I don’t, what I’ve been up to lately. Lord knows what they’ll ultimately publish, so I thought I’d just write this instead.

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16 Questions About Self-Driving Cars | Andreessen Horowitz https://a16z.com/16-questions-about-self-driving-cars/

watch time: 30 minutes Everything that moves, says a16z partner Frank Chen, will go autonomous. But what does that really mean? In this presentation from our a16z Summit, Chen goes over the 16 most commonly asked questions about autonomous cars, and what their answers might be:  Will we progress ...

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Investing in Sesame AI | Andreessen Horowitz https://a16z.com/announcement/investing-in-sesame-ai/

Sesame believes the promise of augmented reality is in the audio, not the display, and it has trained a novel Conversational Speech Model to deliver on this vision.

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Investing in Valar Labs | Andreessen Horowitz https://a16z.com/announcement/investing-in-valar-labs/

There is perhaps nowhere more exciting or impactful to build such tools than in healthcare—where progress is often so constrained by human expertise. Valar Labs is taking on exactly this challenge, and bringing AI into the toolbox for better cancer care.